KLOW Blend

KLOW Blend is a research peptide blend supplied as a single lyophilized preparation containing four synthetic peptides: GHK-Cu (Glycyl-Histidyl-Lysine copper complex, 57.87 mg), BPC-157 (pentadecapeptide, 11.66 mg), KPV (Lys-Pro-Val tripeptide, 9.99 mg), and full-length Thymosin β4 (43-amino-acid peptide, also referred to as TB-500, 11.70 mg) — 80 mg labeled size, 91.22 mg net peptide content per COA. Research Use Only — not for human or veterinary use.

$120.00

Quantity	Price	Discount
5-10	$115.20	4%
11-15	$110.40	8%
16-20	$105.60	12%
21+	$100.80	16%

🧬 99%+ HPLC Purity
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📄 Lot COA Before You Buy
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Description

KLOW Blend is a four-component synthetic peptide blend supplied as a single lyophilized preparation. The four components — GHK-Cu (a copper-binding tripeptide, CAS 89030-95-5, present at 57.87 mg per vial), BPC-157 (a synthetic pentadecapeptide, CAS 137525-51-0, present at 11.66 mg per vial), KPV (the Lys-Pro-Val tripeptide corresponding to residues 11–13 of α-melanocyte-stimulating hormone, CAS 67727-97-3, present at 9.99 mg per vial), and full-length Thymosin β4 (a 43-amino-acid peptide, CAS 77591-33-4, present at 11.70 mg per vial; also referred to in the research-peptide market by the synonym TB-500) — are synthesized independently by solid-phase peptide synthesis (SPPS) and characterized individually by HPLC (purity, 214 nm UV detection) and LC-MS/MS (identity) prior to blending.

This product is supplied as a blue lyophilized powder — the blue color derives from the Cu²⁺ chelate present in the GHK-Cu component. The lot referenced here (Klow-044-TPL) has a documented overall preparation purity of 99.685% and a total net peptide content of 91.22 mg per vial across the four components (labeled 80 mg nominal). Third-party characterization was performed by Freedom Diagnostics (USA). The product is intended exclusively for in-vitro laboratory research and analytical applications.

The four components appear across separate strands of the peer-reviewed literature: GHK-Cu is referenced in extracellular matrix and dermal research (originally characterized in the laboratory of Loren Pickart at UCSF); BPC-157 is referenced in gastrointestinal and connective-tissue in-vivo model research (originally characterized in the laboratory of Predrag Sikirić at the University of Zagreb); KPV is referenced in α-MSH-fragment and anti-inflammatory receptor research; and full-length Thymosin β4 is referenced in cytoskeletal actin-binding and tissue-model research.

Additional information

Product Name	KLOW Blend
Also Known As	KLOW; KLOW peptide blend; KLOW research blend; KLOW 80mg
Composition	GHK-Cu + BPC-157 + KPV + Thymosin β4 (four-component synthetic peptide blend)
Component Ratios (per COA lot Klow-044-TPL)	GHK-Cu 57.87 mg · BPC-157 11.66 mg · KPV 9.99 mg · Thymosin β4 11.70 mg
Labeled Size	80 mg (nominal)
Net Peptide Content per Vial (COA)	91.22 mg (sum of components)
Overall Preparation Purity	99.685% (HPLC with UV detection, coupled with LC-MS/MS)
Appearance	Blue lyophilized powder (color derives from the Cu²⁺ chelate of GHK-Cu)
Solubility	Soluble in water / aqueous buffer
Storage (lyophilized)	-20°C, sealed, protected from light/moisture
Storage (reconstituted)	2–8°C short-term; aliquot & freeze -20°C; avoid freeze-thaw
Synthesis	Each component synthesized independently by SPPS
Testing Lab	Freedom Diagnostics, USA
Principal Chemist (on COA)	Stephen Schmidt
Test Methods	HPLC with UV detection at 214 nm; identity by LC-MS/MS
Lot Number	Klow-044-TPL
Accession Number (COA)	2601130119
Shipped From	USA

Research Context

The following describes investigative contexts in which each component appears in the scientific literature. Provided for scientific background only; this does not describe any product use, and does not describe combined use.

GHK-Cu — used as a reference copper-binding tripeptide in in-vitro dermal fibroblast, extracellular matrix (collagen, glycosaminoglycan), and metallopeptide-signaling assays.
BPC-157 — referenced as a synthetic pentadecapeptide tool compound in in-vitro connective-tissue and cellular model characterization work.
KPV — used as a reference α-MSH C-terminal tripeptide in in-vitro melanocortin-adjacent and NF-κB reporter assays.
Thymosin β4 (full-length) — used as an actin-binding-domain reference peptide in in-vitro cytoskeletal, cell-motility, and connective-tissue model systems.
Analytical method development — multi-peptide blends of this type are used as complex-matrix references in HPLC-UV and LC-MS/MS method development.

Handling & Storage (Labratory)

Reconstitution. Reconstitution solvent should be selected according to your experimental protocol and stability requirements for the peptide components present. Common research-grade options include HPLC-grade ultrapure water or dilute acetic acid. Because this is a multi-component preparation containing peptides with different solubility profiles, validate compatibility with your assay system and confirm solubility of all four components at your working concentration before use. Add solvent slowly down the vial wall; do not shake vigorously, and allow to dissolve fully before use. The blue color characteristic of the GHK-Cu component will remain visible in solution.

Storage — lyophilized. Store sealed at -20°C, protected from light and moisture.

Storage — reconstituted. Store at 2–8°C short-term, or aliquot and freeze at -20°C for longer-term storage. Avoid repeated freeze-thaw cycles. Determine working concentrations using your own validated laboratory methods.

KLOW Blend — Frequently Asked Questions

What is KLOW Blend?

KLOW Blend is a research peptide blend supplied as a single lyophilized preparation containing four synthetic peptides: GHK-Cu, BPC-157, KPV, and full-length Thymosin β4 (also referred to as TB-500). It is supplied for laboratory research use only.

What are the four components of KLOW Blend and their amounts?

Per the lot Certificate of Analysis (lot Klow-044-TPL), KLOW Blend contains GHK-Cu at 57.87 mg, BPC-157 at 11.66 mg, KPV at 9.99 mg, and Thymosin β4 at 11.70 mg per vial. Each component is manufactured independently by solid-phase peptide synthesis and characterized by HPLC (214 nm UV detection) and LC-MS/MS prior to blending. Total net peptide content is 91.22 mg per vial; labeled vial size is 80 mg nominal.

Is KLOW a peptide blend?

Yes. KLOW Blend is a four-component synthetic peptide blend, supplied as a single lyophilized preparation for laboratory research use only.

What are the molecular weights of the KLOW Blend components?

GHK-Cu has an approximate molecular weight of 403.9 g/mol (as the copper complex; ~340.4 g/mol for the GHK peptide alone). BPC-157 has an approximate molecular weight of 1419.5 g/mol. KPV has an approximate molecular weight of 342.4 g/mol. The fourth component in this lot is full-length Thymosin β4 with an approximate molecular weight of 4963.4 g/mol, confirmed on the lot COA by convergent LC-MS/MS charge-state assignments.

Is the fourth component of KLOW Blend TB-500 or Thymosin β4?

The fourth component of KLOW Blend, as documented on the lot Certificate of Analysis, is full-length Thymosin β4 (43 amino acids, molecular weight approximately 4963.4 g/mol). "TB-500" is a widely used synonym for the same compound identity in the research-peptide market and is retained in the product synonyms for search-reference purposes.

Why is KLOW Blend blue?

The blue color of the lyophilized powder derives from the copper (Cu²⁺) chelate present in the GHK-Cu component. This is a characteristic of the copper-peptide chemistry and will remain visible when the material is reconstituted in aqueous buffer.

What size is available and what is the purity?

KLOW Blend is available at 80 mg labeled size per vial, with 91.22 mg total net peptide content documented on the lot COA. Overall preparation purity is 99.685 percent by HPLC with UV detection at 214 nm, with identity confirmed by LC-MS/MS. A lot-specific COA from Freedom Diagnostics (USA) is available.

How should KLOW Blend be stored?

Store lyophilized material sealed at -20C, protected from light and moisture. After reconstitution, store at 2-8C short-term or aliquot and freeze at -20C, avoiding repeated freeze-thaw cycles.

Is a Certificate of Analysis (COA) available?

Yes. Each lot has a Certificate of Analysis from an independent third-party laboratory (Freedom Diagnostics, USA) documenting HPLC purity and LC-MS/MS identity confirmation for each component, tied to the vial lot number. The reference lot for this product line is Klow-044-TPL.

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