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Tesamorelin / Ipamorelin

Tesamorelin / Ipamorelin is a research peptide combination containing Tesamorelin (TH9507), a synthetic GHRH analog, and Ipamorelin, a selective growth hormone secretagogue. Supplied as a ≥99% HPLC-tested lyophilized powder, with a lot-specific third-party COA available before purchase, for in-vitro and laboratory research applications only. Research Use Only — not for human or veterinary use.

Original price was: $129.00.Current price is: $104.00.

Quantity	Price	Discount
5-10	$99.84	4%
11-15	$95.68	8%
16-20	$91.52	12%
21+	$87.36	16%

🧬 99%+ HPLC Purity
🧪 Every Batch 3rd-Party Tested
📄 Lot COA Before You Buy
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🇺🇸 USA Shipped

Description

Tesamorelin / Ipamorelin is a research peptide combination consisting of Tesamorelin (TH9507), a synthetic analog of growth hormone-releasing hormone (GHRH), and Ipamorelin, a synthetic peptide used as a selective growth hormone secretagogue research tool. Tesamorelin incorporates an N-terminal modification designed to enhance stability relative to native GHRH, while Ipamorelin is characterized by its selective interaction with the growth hormone secretagogue receptor (GHS-R).

This product is supplied as a lyophilized powder in multiple sizes, synthesized by solid-phase peptide synthesis (SPPS) and characterized by HPLC for purity and LC-MS for identity, with a lot-specific third-party Certificate of Analysis available before purchase. It is intended exclusively for in-vitro laboratory research and analytical applications.

In the research literature, Tesamorelin and Ipamorelin are referenced as peptide research tools for investigating GHRH/GHRHR and growth hormone secretagogue receptor signaling pathways. Research Use Only — not for human or veterinary use.

Additional information

Compound Name	Tesamorelin
Synonyms	TH9507; (trans-3-hexenoyl)hGHRH(1-44) amide; GHRH analog
CAS Number	218949-48-5
Molecular Formula	C₂₂₁H₃₆₆N₇₂O₆₇S
Molecular Weight	~5135.9 g/mol (some sources 5195.9
Peptide Length	44 amino acids (synthetic)
Structure	Full human GHRH(1-44) sequence; N-terminal trans-3-hexenoic acid (hexenoyl) modification on Tyr-1; C-terminal amide
Research Target	GHRH receptor (GHRHR)
Compound Class	Synthetic N-acylated GHRH analog
Purity	≥99% (HPLC) — see lot COA
Identity	Confirmed by LC-MS
Appearance	White lyophilized powder
Solubility	Soluble in water / aqueous buffer
Available Sizes	5mg, 10mg
Storage (lyophilized)	-20°C, sealed, dark, dry
Storage (reconstituted)	2–8°C short-term; aliquot & freeze -20°C; avoid freeze-thaw
Synthesis	Solid-phase peptide synthesis (SPPS)
Testing Lab	Freedom Diagnostics
Test Methods	Purity by HPLC; identity by LC-MS
Shipped From	USA
Certificate of Analysis	Lot-specific COA available
Size	10mg, 20mg

Tesamorelin — Frequently Asked Questions

What is Tesamorelin?

Tesamorelin (TH9507) is a synthetic 44-amino-acid analog of growth hormone-releasing hormone (GHRH), modified with an N-terminal trans-3-hexenoyl group. It is supplied as a lyophilized powder for laboratory research use only.

What is the molecular weight and CAS number of Tesamorelin?

Tesamorelin has a molecular formula of C₂₂₁H₃₆₆N₇₂O₆₇S, a molecular weight of approximately 5135.9 g/mol, and CAS number 218949-48-5.

What is Tesamorelin's structure?

It comprises the full 44-amino-acid human GHRH(1-44) sequence with a trans-3-hexenoic acid (hexenoyl) modification on the N-terminal tyrosine, which increases resistance to DPP-IV degradation.

What receptor does Tesamorelin target?

In receptor-pharmacology research, Tesamorelin is characterized as an agonist at the GHRH receptor (GHRHR), a Gs-coupled G-protein-coupled receptor.

Is Tesamorelin related to Ipamorelin?

They are distinct compounds studied within growth-hormone-axis research: Tesamorelin is a 44-amino-acid GHRH analog, while Ipamorelin is a pentapeptide. They are sometimes referenced together in the research literature as complementary tool compounds. See our related research compounds for Ipamorelin.

What purity is this Tesamorelin?

This product is ≥99% pure as verified by HPLC, with identity confirmed by LC-MS. A lot-specific Certificate of Analysis from a third-party laboratory is available.

What sizes are available?

This product is available in multiple vial sizes as a research-grade lyophilized powder.

How should Tesamorelin be stored?

Store lyophilized material sealed at -20°C, protected from light and moisture. After reconstitution, store at 2–8°C short-term or aliquot and freeze at -20°C, avoiding repeated freeze-thaw cycles.

Is a Certificate of Analysis (COA) available?

Yes. Each lot has a Certificate of Analysis from an independent third-party laboratory documenting HPLC purity and LC-MS identity confirmation, tied to the vial lot number.

Do you provide dosing or usage instructions?

No. All products are supplied strictly for laboratory research use only. We do not provide dosing, administration, or usage guidance of any kind. Researchers determine experimental parameters according to their own validated protocols and applicable regulations.

Research Context

Provided for scientific background only; this does not describe any product use.

GPCR / receptor pharmacology — used as a reference GHRH-receptor agonist in receptor-binding and cAMP-accumulation assays (GHRHR is a Gs-coupled GPCR).
Peptide-stability / structure studies — a model for N-acylation and DPP-IV-resistance in peptide design.
Signal-transduction research — referenced in in-vitro studies of GHRHR-associated cAMP/PKA/CREB signaling in cell models.
Analytical method development — used as a large-peptide reference in HPLC and MS method development.

Handling & Storage

For laboratory research handling only.

Reconstitution. Tesamorelin is water-soluble. Reconstitution solvent should be selected according to your experimental protocol; common research-grade options include HPLC-grade ultrapure water or bacteriostatic-grade sterile water where multi-day stability is required. Validate compatibility with your assay system before use. Add solvent slowly down the vial wall; do not shake; allow to dissolve fully.

Storage — lyophilized. Sealed at -20°C, protected from light and moisture. (Shelf-stable at ambient during transit; transfer to -20°C promptly on receipt.)

Storage — reconstituted. 2–8°C short-term, or aliquot and freeze -20°C. Avoid repeated freeze-thaw. Determine working concentrations using your own validated laboratory methods.

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