Slu-PP-332 5mg

SLU-PP-332 (SR9861) is a synthetic pan-ERR agonist (small-molecule benzohydrazide, C₁₈H₁₄N₂O₂, CAS 303760-60-3, MW 290.32) supplied as a ≥98% HPLC-tested lyophilized powder, 5 mg per vial, for in-vitro and laboratory research applications only. Research Use Only — not for human or veterinary use.

$50.00

Quantity	Price	Discount
5-10	$48.00	4%
11-15	$46.00	8%
16-20	$44.00	12%
21+	$42.00	16%

🧬 99%+ HPLC Purity
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Description

SLU-PP-332 (also known as SR9861) is a synthetic small-molecule agonist of the estrogen-related receptors (ERRα, ERRβ, and ERRγ), a family of orphan nuclear receptors. Chemically it is a benzohydrazide, (E)-4-hydroxy-N′-(naphthalen-2-ylmethylene)benzohydrazide, with the molecular formula C₁₈H₁₄N₂O₂ and a molecular weight of 290.32 g/mol.

This product is supplied as a lyophilized powder at 5 mg per vial, characterized by HPLC (purity) and LC-MS (identity). It is soluble in DMSO and insoluble in water. It is intended exclusively for in-vitro laboratory research and analytical applications.

In the research literature, SLU-PP-332 is referenced as a reference pan-ERR agonist, reported to interact with ERRα, ERRβ, and ERRγ with EC₅₀ values in the nanomolar range (approximately 98, 230, and 430 nM respectively), with greatest potency at ERRα. It is commonly used as a tool compound in the study of estrogen-related receptor signaling.

Additional information

Compound Name	SLU-PP-332
Synonyms / Also Known As	SR9861; ERR pan-Agonist 332
CAS Number	303760-60-3
Chemical Name (IUPAC)	(E)-4-Hydroxy-N′-(naphthalen-2-ylmethylene)benzohydrazide
Molecular Formula	C₁₈H₁₄N₂O₂
Molecular Weight	290.32 g/mol
Compound Class	Small-molecule benzohydrazide; pan-ERR (estrogen-related receptor) agonist
Research Target	ERRα / ERRβ / ERRγ (estrogen-related receptors)
Purity	≥98% (HPLC) — see lot COA
Identity Confirmation	Confirmed by LC-MS (per lot COA)
Appearance	White lyophilized powder
Solubility	Soluble in DMSO (~58–75 mg/mL); insoluble in water
Vial Contents	5 mg per vial
Storage (powder)	-20°C, sealed, protected from light/moisture
Storage (in solution)	DMSO stock at -20°C, aliquoted; avoid freeze-thaw cycles
Synthesis	Synthetic small molecule
Testing Lab	Freedom Diagnostics
Test Methods	Purity by HPLC; identity by LC-MS
Shipped From	USA
Certificate of Analysis	Lot-specific COA available

SLU-PP-332 — Frequently Asked Questions

What is SLU-PP-332?

SLU-PP-332 (also known as SR9861) is a synthetic small-molecule agonist of the estrogen-related receptors (ERRα, ERRβ, ERRγ). This product is supplied as a lyophilized powder for laboratory research use only.

What is the molecular weight and formula of SLU-PP-332?

SLU-PP-332 has a molecular weight of approximately 290.32 g/mol and the molecular formula C₁₈H₁₄N₂O₂ (CAS 303760-60-3).

What is the chemical name of SLU-PP-332?

Its IUPAC name is (E)-4-hydroxy-N′-(naphthalen-2-ylmethylene)benzohydrazide. It is also referred to as SR9861.

What purity is this SLU-PP-332?

This product is ≥98% pure as verified by HPLC, with identity confirmed by LC-MS. A lot-specific Certificate of Analysis from a third-party laboratory is available.

How is SLU-PP-332 solubilized?

SLU-PP-332 is soluble in DMSO and insoluble in water. Stock solutions are typically prepared in DMSO according to the researcher's experimental protocol.

How should SLU-PP-332 be stored?

Store the powder sealed at -20°C, protected from light and moisture. DMSO stock solutions may be stored at -20°C; aliquot to avoid repeated freeze-thaw cycles.

Is a Certificate of Analysis (COA) available?

Yes. Each lot has a Certificate of Analysis from an independent third-party laboratory documenting HPLC purity and LC-MS identity confirmation, tied to the vial lot number.

Certificate of Analysis (COA)

Certificate of Analysis (COA): Lot-specific COA with HPLC purity and LC-MS identity.

Research Contex

The following describes investigative contexts in which SLU-PP-332 appears in the scientific literature. Provided for scientific background only; this does not describe any product use.

Nuclear receptor pharmacology — used as a reference agonist in ERRα/β/γ receptor-binding and reporter-gene assays.
Estrogen-related receptor signaling research — a tool compound for probing ERR-mediated transcriptional pathways in cell-based models.
Selectivity / structure–activity studies — studied for its receptor selectivity profile across the ERR family and related nuclear receptors.
In-vitro cellular models — referenced in the literature in cell-line studies of ERR target-gene expression (e.g., in C2C12 and HEK293 cell systems).

Handling & Storage

For laboratory research handling only.

Reconstitution. SLU-PP-332 is soluble in DMSO and insoluble in water. Prepare stock solutions in DMSO according to your experimental protocol; dilute into aqueous assay buffer as required by your method, mindful of final DMSO concentration and solubility limits. Validate compatibility with your assay system before use.

Storage — powder. Store sealed at -20°C, protected from light and moisture.

Storage — in solution. DMSO stock solutions may be stored at -20°C; aliquot to avoid repeated freeze-thaw cycles. Determine working concentrations using your own validated laboratory methods.

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